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Creators/Authors contains: "Derrick, Joshua"

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  1. ; ; ; ; (, Scientific Reports)
    Abstract In exponential population growth, variability in the timing of individual division events and environmental factors (including stochastic inoculation) compound to produce variable growth trajectories. In several stochastic models of exponential growth we show power-law relationships that relate variability in the time required to reach a threshold population size to growth rate and inoculum size. Population-growth experiments inE. coliandS. aureuswith inoculum sizes ranging between 1 and 100 are consistent with these relationships. We quantify how noise accumulates over time, finding that it encodes—and can be used to deduce—information about the early growth rate of a population. 
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  2. ; ; ; (, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids)
    The intestine is responsible for efficient absorption and packaging of dietary lipids before they enter the circulatorysystem. This review provides a comprehensive overview of how intestinal enterocytes from diverse model organisms absorb dietary lipid and subsequently secrete the largest class of lipoproteins (chylomicrons) to meet the unique needs of each animal. We discuss the putative relationship between diet and metabolic disease progression, specifically Type 2 Diabetes Mellitus. Understanding the molecular response of intestinal cells to dietary lipid has the potential to undercover novel therapies to combat metabolic syndrome. 
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